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Ebola Virus Outbreak

Growing Ebola Outbreak Threatens to Overwhelm Volunteers

Augustine Goba, head of the Viral Hemorrhagic Fever laboratory at Kenema Government Hospital in Sierra Leone, works on suspected Ebola samples. Dr Robert Garry / Robert Garry/Tulane University

When a team from Tulane University sent a batch of protective clothing and equipment to help workers fighting an outbreak of Ebola virus in Sierra Leone last month, they were fairly confident the 300 or so packs would be enough for a good start.

They couldn’t have predicted what they would be up against.

The World Health Organization says 22 new cases of Ebola virus were reported in Sierra Leone between May 29th and June 5. WHO counts 81 cases with 6 deaths but Sierra Leone’s health ministry says it has a total of 95 confirmed and suspected cases.

“This is worse than expected. I am fearful that it could get much worse,” said Robert Garry, a virologist and specialist in viral hemorrhagic fevers at Tulane University. Garry flew to Kenema Government Hospital last month with as much personal protective equipment (PPE) as he could carry, but he says they are running out fast.

"We have to ration them," he said.

Nurse Veronica Koroma stands in the doorway of the Viral Hemorrhagic Fever (VHF)  ward at Kenema Government Hospital in Sierra Leone.
Nurse Veronica Koroma stands in the doorway of the Viral Hemorrhagic Fever (VHF) ward at Kenema Government Hospital in Sierra Leone. Robert Garry/Tulane University / Robert Garry/Tulane University

Kenema Hospital is treating 11 patients with Ebola, all being kept in isolation. Six more have died. With each worker needing a complete change of gown, mask, gloves, goggle and other protective gear with each visit, that means supplies go fast.

At least 35 lab-confirmed Ebola cases have been traced to a traditional healer whose grieving patients apparently handled her body at her funeral and became infected themselves, Garry says.

The healer had treated patients just over the border in neighboring Guinea. This cross-border outbreak is worrying health officials because it's spreading in an area where people cross from one country into another casually, passing through large cities on their travels.

Ebola is one of the deadliest viruses known. It kills quickly, taking anywhere between 50 percent and 90 percent of victims, depending on the strain.

The good news is it doesn’t spread terribly easily — it requires direct contact with bodily fluids. But caregivers and health care workers can become infected while caring for patients, and funeral rituals such as washing a body can expose more people.

“Community resistance is hindering the identification and follow-up of contacts."

And if people don’t know they’ve been exposed, they can travel sometimes long distances to spreads the virus to others when they themselves become ill. WHO says experts are trying to track down 30 people now.

“Community resistance is hindering the identification and follow-up of contacts,” WHO says.

“They are just scattering,” Garry confirmed. “It’s very hard to track them down.” Garry's working with local and international experts to identify cases, distribute protective gear, train workers and test samples.

"Unfortunately, these numbers will rise dramatically as cases from the Koindu and Daru regions are tallied. Reports from the field for villages surrounding Koindu and Daru are grim."

The outbreak started in Guinea earlier this year, the first time Ebola had been seen in West Africa. WHO says at least 21 people died and 48 new cases of suspected Ebola were recorded in Guinea between May 29 and June 3, taking Guinea’s total to 344.

With more than 215 deaths so far, the West African outbreak is one of the worst on record.

Ebola first arose in Zaire, now the Democratic Republic of Congo, in 1976. In that outbreak, 318 people were sickened and 280 died, with a mortality rate of 88 percent. The biggest outbreak affected 425 people in Uganda in 2000, killing 224 of them.

Education is the key to fighting it. Garry says many people in affected regions don’t understand it’s a virus and often don’t believe advisories about how it’s spread. His team is educating health care workers so they can protect themselves and teach others.

A poster used to educate health care workers in Sierra Leone about symptoms of Ebola virus.
A poster used to educate health care workers in Sierra Leone about symptoms of Ebola virus. A team from Tulane University is working with at Kenema Government Hospital to help fight the outbreak. Robert Garry/Tulane University / Courtesy of Robert Garry

“They pay attention once they hear how it’s spread,” Garry said. “The idea is to train these people here to go back and disseminate the main instructions about the disease.”

An Ebola infection often looks like malaria at first, so people may not suspect they have it. It later progresses to the classic symptoms of a hemorrhagic fever, with vomiting, diarrhea, high fever and both internal and external bleeding.

With so many bodily fluids pouring from a patient, it is easy to see how caregivers could become infected.

“They pay attention once they hear how it’s spread."

“Ebola is a disease that scares people and that is perceived as mysterious, but people can overcome it,” says Marie-Christine Ferir, emergency coordinator for the group Medecins Sans Frontieres, or Doctors Without Borders. “Earning people’s trust is essential in efforts to fight the epidemic."

WHO says six experts and 5,000 sets of protective equipment have been sent to Sierra Leone by various groups.

Garry says his team is building on years of groundwork. He's been working with the Kenema hospital for a decade to build its capacity to fight another viral hemorrhagic fever, Lassa.

Lassa fever is a serious problem in West Africa, making between 100,000 to 300,000 people sick every year and causing 5,000 deaths. It can also cause hemorrhagic symptoms, although it is far less deadly than Ebola, killing 20 percent of patients sick enough to be hospitalized and 1 percent of patients overall.

Protective measures for health care workers treating patients with Lassa fever or Ebola are the same.

“We tell them to wear gloves and to protect their eyes,” Garry said, speaking by telephone from the hospital. “And we’ve shown people how to do a traditional burial, only wearing gloves. And you can allow the body to be washed briefly. Workers have been attentive to the traditions, allowing the body to be wrapped without exposing people to the virus.”

Genetic analysis of the virus causing the current outbreaks show it’s distinct from the virus seen in east Africa. This suggests it may be from a local source. No one’s sure just where Ebola cames from. It can affect great apes but fruit bats are a prime suspect.

Garry, who was only scheduled to stay for a couple of weeks, now says he is not sure when he can leave. "I don't think it's going to be soon," he said.