updated 4/8/2011 12:45:33 PM ET 2011-04-08T16:45:33

ST. LOUIS, April 8, 2011 (GLOBE NEWSWIRE) -- Sigma-Aldrich Corporation (Nasdaq:SIAL) will hold its quarterly conference call to discuss first quarter results on April 26, 2011 at 10:00 AM Central (11:00 AM Eastern).

Date: April 26, 2011
Time: 11:00 AM ET
Toll-Free: 877-266-0483
International: 707-287-9342
Passcode: 37556229

Webcast and slide presentation via Internet: http://investor.sigmaaldrich.com/

Replay Information:

Toll Free:  800-642-1687
International:  706-645-9291
Passcode:  37556229

Sigma-Aldrich is a leading Life Science and High Technology company committed to Enabling Science to Improve the Quality of Life. Its chemical and biochemical products and kits are used in scientific research, including genomic and proteomic research, biotechnology, pharmaceutical development and as key components in pharmaceutical, diagnostic and other high technology manufacturing. The Company has customers in life science companies, university and government institutions, hospitals, and in industry. More than one million scientists and technologists use its products. Sigma-Aldrich operates in 40 countries and has 7,900 employees providing excellent service worldwide. For more information about Sigma-Aldrich, please visit its award-winning website at http://www.sigma-aldrich.com.

CONTACT: Carrie Fields
         Investor Relations
         carrie.fields@sial.com
         314-286-8015

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