Image: A photo made from NASA video shows the Endeavour docked on the Harmony node of the International Space Station
NASA via AP
A photo made from NASA video shows the Endeavour docked on the Harmony node of the International Space Station, Wednesday May 18, 2011 on the penultimate voyage of the space shuttle program. It is carrying a particle physics detector for the station. (AP Photo/NASA)
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updated 5/18/2011 4:53:15 PM ET 2011-05-18T20:53:15

The space shuttle Endeavour arrived for one last visit to the International Space Station on Wednesday after a two-day orbital chase.

Endeavour and its six astronauts docked at the orbiting laboratory at 6:14 a.m. ET.

"Endeavour arriving," Paolo Nespoli, an Italian astronaut on the space station, said as the shuttle connected with the outpost.

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It took the crews on both the station and shuttle another two hours to check for leaks in the seal between their two spacecraft. Then the doors were opened and the shuttle astronauts floated through.

"Hey, you guys wore coordinating shirts. We didn't do that," shuttle commander Mark Kelly said as he climbed aboard the space station. "It's good to be back. It looks pretty much the same."

Kelly last saw the International Space Station in 2008 during his STS-124 shuttle mission. During Wednesday's greetings, he and the other spacefliers welcomed each other with hugs and handshakes.

Endeavour made its last liftoff Monday morning, beginning a 16-day mission to orbit. The shuttle will stay at the space station until May 29, when it will undock to begin the trek back to Earth for good. [Photos of Shuttle Endeavour's Final Launch]

Doubling the population
Kelly's crewmates aboard Endeavour include pilot Greg Johnson, Michael Fincke, Andrew Feustel, Greg Chamitoff and Italian astronaut Roberto Vittori. [Video: Endeavour's Liftoff into History]

Their addition to the space station doubles the outpost's population. Currently living aboard the station with Nespoli as part of the Expedition 27 mission are commander Dmitri Kondratyev of Russia, and flight engineers Ron Garan and Catherine Coleman of NASA, and Russian cosmonauts Alexander Samokutyaev and Andrey Borisenko.

The station residents were excited to have visitors.

"Yoo Hoo house-guests!" Garan wrote via Twitter on Tuesday.

Busy mission
The main goal of Endeavour's final mission is to deliver an astrophysics experiment called the Alpha Magnetic Spectrometer to the International Space Station. At $2 billion, it's the most expensive science experiment ever flown to the station, and offers the potential to solve numerous cosmic mysteries, such as what constitutes the invisible dark matter thought to pervade the universe.

Image: Space shuttle Endeavour
NASA TV
The space shuttle Endeavour approaches the International Space Station shortly before Wednesday's docking.

Endeavour is also packed with spare supplies for the space station, including extra ammonia coolant, antenna systems and parts for the station's Dextre robot.

The shuttle's crew plans four busy spacewalks and a host of intensive robotic arm maneuvers to stow the parts and perform maintenance on the exterior of the station.

The graveyard shift
Endeavour's astronauts are working the overnight shift during their mission, relative to Mission Control time in Houston.

The crew woke Tuesday evening at 10:56 p.m. ET to the song "Drops of Jupiter" by the band Train. The tune was selected for Johnson by his family and radioed up to the shuttle by Mission Control.

"I love that song and I love being in space," Johnson said. He thanked his teenage son Matt for the choice, and apologized for missing his birthday, which is Thursday. "And I want to say that's a perfect way to start an exciting rendezvous day!"

Backflip in space
Early Tuesday, the astronauts spent their first full workday in space conducting a detailed inspection of their orbiter's heat shield tiles to check for any damage that might have been suffered during launch.

So far, the sensitive tiles appear to be in good shape to protect the shuttle from the fiery heat of atmospheric re-entry.

"Preliminary assessment is it looks really good so far," LeRoy Cain, head of Endeavour's mission management team, said during a news briefing Tuesday. "We're not tracking any issues as far as that's concerned."

Another check of the heat shield will be available soon, when Mission Control has a chance to analyze high-resolution photos taken of the shuttle's underbelly as it approached the station.

When Endeavour was about 600 feet (180 meters) below the space station, Kelly steered the shuttle through a backflip that exposed the orbiter's heat shield to the station, allowing astronauts there to snap hundreds of detailed images. The operation is called the Rendezvous Pitch Maneuver.

Analysis of the photos should be complete in the coming days.

You can follow Space.com senior writer Clara Moskowitz on Twitter @ClaraMoskowitz.Visit Space.com for complete coverage of Endeavour's final mission STS-134 or follow us @Spacedotcom and on Facebook.

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Interactive: Endeavor's final mission

  1. Above: Interactive Endeavor's final mission
  2. Timeline Space shuttle timeline

Video: Endeavour comes home for good

Photos: The life of space shuttle Endeavour

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  1. Special delivery

    Endeavour was the last space shuttle to join NASA's fleet: It was built to replace the shuttle Challenger, which was lost in an explosion shortly after launch in 1986. This view shows Endeavour perched atop a modified Boeing 747 on May 2, 1991, beginning the ferry flight from Palmdale, Calif. - where the shuttle was built - to Kennedy Space Center in Florida. (NASA) Back to slideshow navigation
  2. First liftoff

    Endeavour lifts off from Launch Pad 39B at NASA's Kennedy Space Center on May 7, 1992, beginning its first mission. The STS-49 mission's primary task was the repair of the Intelsat VI telecommunications satellite. Endeavour was the only shuttle to make its maiden flight from Pad 39B. (NASA) Back to slideshow navigation
  3. Grab that satellite!

    Endeavour astronauts Richard Hieb, Thomas Akers and Pierre Thuot hold onto the 4.5-ton Intelsat VI satellite after making a six-handed "capture" on May 13, 1992. The satellite failed to rise above low Earth orbit when it was launched in 1990. During Endeavour's maiden mission, astronauts retrieved the satellite, attached it to a new upper-stage booster and relaunched it to its intended geosynchronous orbit. This mission marked the first time that three people from the same spacecraft walked in space at the same time. (NASA) Back to slideshow navigation
  4. Science in space

    Endeavour astronauts Jan Davis, left, and Mae Jemison prepare to deploy the lower body negative pressure apparatus on Sept. 15, 1992. Scientific research was the main focus of this Spacelab-J mission, also known as STS-47. The mission's crew included the first African-American woman to fly in space (Mae Jemison) and the only husband-and-wife team to go into space together (Jan Davis and Mark Lee). (NASA) Back to slideshow navigation
  5. Fixing Hubble

    Astronauts flew on Endeavour to take on the first Hubble servicing mission in December 1993. In this picture, spacewalkers Story Musgrave and Jeffrey Hoffman perform an orbital ballet. The coastline of western Australia is visible below. The complex and highly successful repair mission allowed Hubble, which was launched with a defective mirror, to see into the universe with unprecedented clarity. (NASA) Back to slideshow navigation
  6. Building the station

    Endeavour spacewalker Jim Newman holds onto the International Space Station's Unity connecting module as he removes covers and works on connecting cables on Dec. 7, 1998. The STS-88 flight marked the shuttle fleet's first space station assembly mission. (AFP/Getty Images) Back to slideshow navigation
  7. Erroneous endeavor

    The shuttle Endeavour sits on its launch pad at Kennedy Space Center in Florida on July 11, 2007. "Endeavor" is spelled incorrectly on the banner. The shuttle was named after the HMS Endeavour, the British sailing ship that carried Captain James Cook on his first voyage of discovery from 1768 to 1771. That's why Endeavour reflects the British spelling of the word. (Eliot J. Schechter / Getty Images) Back to slideshow navigation
  8. Spacewalkers at work

    During the first spacewalk of the STS-118 mission, on Aug. 11, 2007, astronaut Rick Mastracchio and Canada's Dave Williams (out of frame) attach a new segment of the International Space Station's truss and retract a collapsible radiator. (NASA) Back to slideshow navigation
  9. Class portrait

    The crew members of Endeavour's STS-118 crew pose for their official portrait on Aug. 8, 2007. From left are Rick Mastracchio, Barbara Morgan, pilot Charles Hobaugh, mission commander Scott Kelly, Tracy Caldwell, Canadian astronaut Dave Williams and Alvin Drew. During this flight, Morgan became the first educator astronaut to go into orbit. In 1986, she was the backup for Christa McAuliffe, the New Hampshire teacher who died in the Challenger explosion. (NASA) Back to slideshow navigation
  10. Great view

    Endeavour spacewalker Rick Mastracchio relocates communications equipment on the International Space Station during an outing on Aug. 15, 2007. (NASA) Back to slideshow navigation
  11. A gouge in the tiles

    Tiles on the underside of the space shuttle Endeavour show evidence of damage in a photo taken on Aug. 12, 2007, using the shuttle's robotic arm and a camera-tipped extension boom. The close-up imagery helped mission managers determine that the gouge would pose no threat during Endeavour's atmospheric re-entry. (NASA via AP) Back to slideshow navigation
  12. Eye of the hurricane

    Crew members aboard the shuttle Endeavour captured this picture of Hurricane Dean's eye in the Caribbean on Aug. 18, 2007. The STS-118 mission ended on Aug. 21, one day earlier than planned, to avoid potential complications due to the storm. Forecasters worried that Hurricane Dean could have swept over Houston around the time of landing - but in the end, the storm took a different course. (NASA) Back to slideshow navigation
  13. In control

    NASA Administrator Michael Griffin watches the liftoff of the space shuttle Endeavour from the Launch Control Center at NASA's Kennedy Space Center on Nov. 14, 2008. The STS-126 mission delivered two spare bedrooms as well as a second kitchen and bathroom to the International Space Station. (Bill Ingalls / NASA) Back to slideshow navigation
  14. Repairs at the pad

    Workers perform repairs on the shuttle Endeavour's external fuel tank at the Kennedy Space Center launch pad on June 14, 2009. The launch team detected a leak of hydrogen fuel from the tank, forcing a delay in Endeavour's STS-127 launch. The mission's main task was the delivery of the final segment of Japan's Kibo laboratory to the International Space Station. (Tim Jacobs / NASA) Back to slideshow navigation
  15. Lightning strikes

    A giant bolt of lightning hits Endeavour's Florida launch pad on July 10, 2009. Technical problems and severe weather forced five delays in Endeavour's STS-127 launch. (Gene Blevins / Zuma Press) Back to slideshow navigation
  16. Liftoff at last!

    The space shuttle Endeavour rises from Kennedy Space Center's Launch Pad 39A on July 15, 2009, on the STS-127 mission's sixth launch attempt. (NASA) Back to slideshow navigation
  17. Parting glance

    The space shuttle Endeavour is photographed from the International Space Station soon after its departure on July 28, 2009. A Soyuz spacecraft docked at the station is visible in the foreground. (NASA) Back to slideshow navigation
  18. Twilight of the shuttle

    The shuttle Endeavour is silhouetted against different layers of the sunlit atmosphere during its approach to the International Space Station on Feb. 9, 2010. The primary payloads for Endeavour's STS-130 mission were the Tranquility module and the Cupola observation deck and control station. (NASA) Back to slideshow navigation
  19. Check out this view!

    Astronaut George Zamka, Endeavour's commander for the STS-130 mission, peeks out a window of the International Space Station's newly installed Cupola observation deck on Feb. 19, 2010. The Cupola provides an unparalleled view of Earth below. (NASA) Back to slideshow navigation
  20. Tanks for the memories

    The external fuel tank for Endeavour's final mission, STS-134, is transported to the Vehicle Assembly Building at the Kennedy Space Center in Florida on July 14, 2010. STS-134's main payload is the $2 billion Alpha Magnetic Spectrometer, an international physics experiment. (John Raoux / AP) Back to slideshow navigation
  21. The view from above

    The space shuttle Endeavour is lowered into place for attachment to its external fuel tank and solid rocket boosters in the Vehicle Assembly Building at NASA's Kennedy Space Center in Florida on March 1, 2011. (NASA via Getty Images) Back to slideshow navigation
  22. Greeting the day

    The sun rises as photographers gather on a hill to take pictures shortly after the shuttle Endeavour's arrival at Kennedy Space Center's Launch Pad 39A on March 11, 2011. (Roberto Gonzalez / Getty Images) Back to slideshow navigation
  23. Into the clouds

    Photographers track the space shuttle Endeavour's ascent as it pierces the clouds and disappears after launch from NASA's Kennedy Space Center in Florida on May 16. (Craig Rubadoux / Daytona Beach News-Journal via AP) Back to slideshow navigation
  24. Godspeed, Endeavour!

    Spectators react as the space shuttle Endeavour lifts off from NASA's Kennedy Space Center in Florida on May 16. Hundreds of thousands of people watched the start of the next-to-last space shuttle flight. (Scott Audette / Reuters) Back to slideshow navigation
  25. Above the clouds

    Stefanie Gordon captured this remarkable picture of the space shuttle Endeavour rising above Florida's cloud cover on May 16 while she was on a commercial flight from New York to Palm Beach, Fla. (Stefanie Gordon / for msnbc.com) Back to slideshow navigation
  26. The last spacewalk

    NASA astronaut Greg Chamitoff holds a handrail during the fourth and last spacewalk conducted by the shuttle Endeavour's crew at the International Space Station on May 27. Chamitoff and astronaut Michael Fincke (visible in the reflections from Chamitoff's helmet visor) transferred an inspection boom system, completing U.S. assembly of the station. The May 27 outing marked the last scheduled spacewalk to be conducted by a space shuttle crew. (Nasa T.V. via EPA) Back to slideshow navigation
  27. Night passage

    Backdropped by a nighttime view of Earth and the starry sky, the space shuttle Endeavour is seen docked to the International Space Station on May 28. (NASA via Reuters) Back to slideshow navigation
  28. Landing in the dark

    The space shuttle Endeavour lands for the last time at NASA's Kennedy Space Center in Florida on June 1, 2011. The touchdown capped Endeavour's 16-day mission to deliver a $2 billion science experiment to the International Space Station on NASA's next-to-last shuttle flight. (Joe Skipper / Reuters) Back to slideshow navigation
  29. Blastoff into history

    A NASA poster pays tribute to Endeavour and its space missions over the past two decades. The shuttle is shown rising to orbit, with patches for each of its missions laid out in a spiral. The HMS Endeavour, which inspired the spaceship's name, is shown at lower right. At upper left, pictures of Endeavour are framed in the windows of the Cupola. The background image depicts the nebula NGC 602 as seen by the Hubble Space Telescope, which was first serviced by Endeavour in 1993. (NASA) Back to slideshow navigation
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