updated 6/16/2011 7:46:42 AM ET 2011-06-16T11:46:42

LIVINGSTON, N.J., June 16, 2011 (GLOBE NEWSWIRE) -- Milestone Scientific Inc. (OTCQB:MLSS), the recognized leader in advanced drug delivery technologies, today announced that it has retained Crescendo Communications, LLC ("Crescendo") as its investor relations advisor.

Leonard Osser, Chief Executive Officer of Milestone Scientific, stated, "Crescendo brings a fresh approach to investor relations and an expertise in working with emerging growth companies in the small cap arena. The hands-on involvement of the firm's principals and their extensive network of seasoned investors in key financial markets around the country make them the ideal advisor and communications partner for our company as we move into the next phase of our growth."

David Waldman, President of Crescendo Communications, commented, "We are pleased to be working with Milestone Scientific whose patented, award-winning, computer-controlled painless injection technology is changing the status quo in dental practices around the world. Moreover, their new distribution strategy of targeting group dental practices is gaining significant traction. Management envisions further expansion of this FDA-approved technology for other medical uses such as epidurals, osteoarthritis and for its self-administered injection system for drug delivery for the anti-immune system.   We look forward to bringing the Milestone Scientific story to the investment community and keeping investors informed of the latest news and developments."

About Crescendo Communications, LLC (www.crescendo-ir.com)

Crescendo Communications, LLC, headquartered in New York City with offices in Beijing, Shanghai and Moscow, is an emerging leader within the investor relations industry. The principals of Crescendo have represented hundreds of companies across all market caps and industries. The firm was founded on a strategic and professional approach to investor relations that builds awareness of public companies through tailored outreach programs that target institutional investors, analysts, and the financial media. Crescendo's approach is centered around properly educating investors and cultivating trust between the firm's clients and the Wall Street community.

About Milestone Scientific Inc.

Headquartered in Livingston, New Jersey, Milestone Scientific is engaged in pioneering advanced computer-controlled drug delivery technologies for the medical and dental markets; and currently sells its award-winning products through a global distribution network serving North and South America, Asia, Africa, Europe and the Middle East. For more information on the STA System and other innovative Milestone products, please visit the Company's websites found at www.milestonescientific.com and www.STAis4u.com.

Safe Harbor Statement

This press release contains forward-looking statements regarding the timing and financial impact of Milestone's ability to implement its business plan, expected revenues and future success. These statements involve a number of risks and uncertainties and are based on assumptions involving judgments with respect to future economic, competitive and market conditions and future business decisions, all of which are difficult or impossible to predict accurately and many of which are beyond Milestone's control. Some of the important factors that could cause actual results to differ materially from those indicated by the forward-looking statements are general economic conditions, failure to achieve expected revenue growth, changes in our operating expenses, adverse patent rulings, FDA or legal developments, competitive pressures, changes in customer and market requirements and standards, and risk factors detailed from time to time in Milestone's periodic filings with the Securities and Exchange Commission, including without limitation, Milestone's Annual Report for the year ended December 31, 2010. The forward-looking statements in this press release are based upon management's reasonable belief as of the date hereof. Milestone undertakes no obligation to revise or update publicly any forward-looking statements for any reason.

CONTACT: David Waldman or Klea Theoharis
         Crescendo Communications, LLC
         mlss@crescendo-ir.com
         212-671-1020

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