Image: Dead frogs
Vance T. Vredenburg
Dead southern mountain yellow-legged frogs (Rana muscosa) killed by the chytrid fungus in the Sierra Nevada in California.
By LiveScience Senior Writer
updated 4/25/2012 8:02:26 PM ET 2012-04-26T00:02:26

A fungus that has torn through frog populations worldwide kills by dehydrating the hapless amphibians, disrupting electrolyte balance and causing cardiac arrest.

The fungus Batrachochytrium dendrobatidis, which is responsible for chytridiomycosis disease, has caused massive frog death on a global scale, threatening many species with extinction. When the fungus reached the Sierra Nevada mountains in California, it slashed mountain yellow-legged frog populations by more than 75 percent in only about four years. The frog (Rana muscosa) is now listed as endangered.

Laboratory experiments had established how the fungus operates, but a new study is the first to observe the disease in action in the wild. San Francisco State University biologist Vance Vredenburg and colleagues collected blood samples and skin swabs from more than 100 yellow-legged frogs over the course of the summer of 2004, the year the outbreak hit the Sierra region.

  1. Science news from
    1. NOAA
      Cosmic rays may spark Earth's lightning

      All lightning on Earth may have its roots in space, new research suggests.

    2. How our brains can track a 100 mph pitch
    3. Moth found to have ultrasonic hearing
    4. Quantum network could secure Internet

"It's really rare to be able to study physiology in the wild like this, at the exact moment of a disease outbreak," study researcher Jamie Voyles, a University of California Berkeley ecologist, said in a statement. The researchers reported their work April 25 in the journal PLoS ONE.

The findings confirmed what researchers had seen in the lab: Infection by the fungus seems to disrupt the frogs' balance of fluids and electrolytes, which are minerals found in the blood that are crucial for muscle function, proper blood pH and hydration.

"The mode of death discovered in the lab seems to be what's actually happening in the field," Vredenburg said in a statement, "and it's that understanding that is key to doing something about it in the future."

In the lab, the disease is easy to treat with antifungal drugs, Vredenburg said. But transferring that treatment to the wild is difficult. Biologists are now experimenting with ways to treat wild frogs. The new research suggests that treating individual frogs with electrolyte supplements could offer a glimmer of hope for survival, Vredenburg said.

Researchers are also working to understand how the disease spreads in the wild. Pacific chorus frogs may be carriers of the disease, according to research published in March in the journal PLoS ONE.

You can follow LiveSciencesenior writer Stephanie Pappas on Twitter @sipappas. Follow LiveScience for the latest in science news and discoveries on Twitter @livescienceand on Facebook.

© 2012 All rights reserved.


Discussion comments


Most active discussions

  1. votes comments
  2. votes comments
  3. votes comments
  4. votes comments