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Hillary Clinton Tweets Late-Night Swipe at Donald Trump a Day After His Rant

Politics makes strange bedfellows — but you wouldn't know it based on tweets sent at all hours of the night from the presidential nominees' Twitter accounts.

A tweet from Hillary Clinton's account in the wee hours of Saturday morning read: "It's 3:20am. As good a time as any to tweet about national service," and linked to a post she wrote on Medium.com titled "Building on what makes America great."

The tweet, which her campaign confirmed to NBC News was posted by an East Coast staffer in real-time, was a jab at Republican rival Donald Trump's own headline-making Twitter rant that started Friday morning at 3:20 a.m.

Trump's angry online barrage was directed at Alicia Machado, the former Miss Universe who he had already been feuding with over comments he made about her weight.

By 5:30 a.m., the outburst had devolved into accusations that Machado had a sex tape; and that Clinton helped her gain U.S. citizenship for the Democratic nominee's own benefit.

Related: Analysis: Examining Trump's Double Standard for Women

"Did Crooked Hillary help disgusting (check out sex tape and past) Alicia M become a U.S. citizen so she could use her in the debate?" Trump tweeted.

The tweets didn't go over well, particularly among feminists.

Clinton described the "meltdown" as "unhinged, even for him."

Trump: No regrets about late-night tweet rant 17:38

"Who gets up at 3 o'clock in the morning to engage in a Twitter attack against a former Miss Universe?" Clinton asked a rally Friday in Coral Springs, Florida. "Really, why does he do things like that?"

Trump defended the tweets.

"Why would I have regrets? I'm a very truthful person, and I'm telling the truth," he told The New York Times.