Oprah Winfrey plays Annie Lee Cooper in "Selma" a 54-year-old woman who punched the notoriously racist county sheriff Jim Clark after he denied her the right to register to vote. The film chronicles the three-month period in 1965, when Dr. Martin Luther King, Jr. led a dangerous campaign to secure equal voting rights in the face of violent opposition. Oprah Winfrey produces
Jason Reed / Reuters
Oprah Winfrey holds up her hand during a ceremony marking the 50th anniversary of Martin Luther King's "I have a dream" speech on the steps of the Lincoln Memorial in Washington August 28, 2013.
Anne Marie Fox / AP
Oprah Winfrey isn't just a talk-show host. Her acting has been critically acclaimed. She received a Screen Actors Guild nomination for playing the wife of White House butler Cecil Gaines (Forest Whitaker) in "The Butler" in 2013.
Mandel Ngan / AFP - Getty Images
President Barack Obama presents the Presidential Medal of Freedom to broadcast journallist Oprah Winfrey during a ceremony in the East Room of the White House on November 20, 2013 in Washington, DC.
Kiichiro Sato / AP
Winfrey acknowledges fans during a star-studded taping of "Surprise Oprah! A Farewell Spectacular," in Chicago on Tuesday, May 17, 2011. Her famed talk show went off the air after 25 years as Winfrey moves to her OWN network.
M. Spencer Green / AP
In one of his last acts before leaving office, Chicago Mayor Richard M. Daley presents Winfrey with a sign after a street was named in her honor outside her Harpo Studios in Chicago on Wednesday, May 11, 2011.
Charles Dharapak / AP
President Barack Obama and first lady Michelle Obama are pictured with Winfrey during a taping of one of her last shows in Chicago on Wednesday, April 27, 2011. Winfrey memorably cried tears of joy when Obama was elected.
Mary Altaffer / AP
Winfrey, chairman of OWN: The Oprah Winfrey Network, announces the new original programming for the channel's Jan. 1, 2011 launch to members of the advertising and media communities on Thursday, April 8, 2010 in New York.
George Burns / AP
Oprah Winfrey wears sunglasses and holds a hair bow given to her by Lady Gaga, left, after a live broadcast of "The Oprah Winfrey Show" on Friday, Jan. 15, 2010 in Chicago.
Fred Prouser / Reuters
Executive producers Tyler Perry, right, and Oprah Winfrey walk the red carpet at the AFI Fest 2009 gala screening of their new film "Precious: Based on the Novel 'Push' by Sapphire" in Hollywood on Nov. 1, 2009.
Charles Dharapak / AP
First lady Michelle Obama, left, sits next to Winfrey and Chicago Mayor Richard M. Daley, right, at the opening ceremonies of the 121st International Olympic Committee (IOC) Session and XIII Olympic Congress at the Copenhagen Opera House on Oct. 1, 2009, in Copenhagen. Despite the star power backing its bid to host the 2016 Olympics, Chicago was eliminated during the first round.
Kiichiro Sato / AP
Winfrey, right, performs with the Black Eyed Peas' Fergie, center, and will.i.am, left, in Chicago on Sept. 8, 2009, while taping an episode of "The Oprah Winfrey Show." The episode was taped on a three-block stretch of Michigan Avenue near the Chicago River to celebrate the show's 24th season.
John Rottet / AP
Winfrey smiles at Duke president Richard Brodhead after receiving her honorary degree from Duke University during a graduation ceremony in Durham, N.C., on May 10, 2009. Her godson, William Bumpus, son of her well-known friend, Gayle King, was among the graduates.
Katy Winn / Getty Images
Oprah Winfrey arrives at the 17th Annual Women In Entertainment Power 100 Breakfast at the Beverly Hills Hotel in Los Angeles on Dec. 5, 2008. Winfrey was No. 1 on the list, which is compiled by the Hollywood Reporter.
George Burns / Harper Productions via AP
Winfrey holds a copy of her September 2008 pick for her Book Club -- David Wroblewski's "The Story of Edgar Sawtelle." Since launching her Book Club in 1996, Winfrey has helped authors from Toni Morrison to Joyce Carol Oates sell millions of books.
Dylan Martinez / Reuters
Winfrey arrives for the birthday dinner party of former South African President Nelson Mandela at Hyde Park in London on June 25, 2008.
Harpo Productions via Reuters
In another first for the talk-show maven, Winfrey endorsed Sen. Barack Obama for president in 2007. She hosted a fundraiser for Obama, accompanied by his wife Michelle, on Sept. 8, 2007, at her home in Montecito, Calif. That weekend, Winfrey made four joint appearances with Obama at various campaign stops.
Denis Farrell / AP
On Jan. 2, 2007, Winfrey, center, cut the ribbon at the opening ceremony of her Leadership Academy for Girls School in South Africa. "The school will teach girls to be the best human beings they can ever be; it will train them to become decision-makers and leaders; it will be a model school for the rest of the world," Winfrey wrote on the academy's Web site.
Jason Decrow / AP
David Letterman walks hand-in-hand with Winfrey from the Ed Sullivan Theater to the premiere of her new musical "The Color Purple" at the nearby Broadway Theater after Winfrey made an appearance on "The Late Show with David Letterman" on Dec. 1, 2005, in New York. For years Letterman had a running joke about how Oprah didn't like him.
Chris Pizzello / AP
Winfrey, right, and actress Halle Berry strike a pose for the cameras on the red carpet at the 77th Academy Awards in Los Angeles on Feb. 25, 2005.
Carlo Allegri / Getty Images
Winfrey brought her own camcorder to the 30th Annual People's Choice Awards on Jan. 11, 2004, in Pasadena, Calif.
Dave Benett / Getty Images
Winfrey joined U2 frontman and philantrophist Bono at a gala dinner before the "Give 1 Minute to AIDS" concert for The Nelson Mandela Foundation's 46664 campaign held at Greenpoint Stadium on Nov. 27, 2003, in Cape Town, South Africa.
Evan Agostini / Getty Images
Winfrey was inducted into the Broadcasting & Cable Magazine Hall of Fame on Nov. 11, 2002. She attended the gala at the Marriott Marquis in New York City.
Benny Gool / AP
Winfrey stands in front of hundreds of children in Durban, South Africa, on Dec. 8, 2002. Tens of thousands of children received gifts of food, clothing, athletic shoes, school supplies, books and toys as part of Winfrey's philanthropic trip for her charity, the Oprah Winfrey Foundation.
George Burns / AP
Actor Tom Cruise appeared on Winfrey's show on Dec. 6, 2001, to talk about his film "Vanilla Sky" and his break-up with then-wife Nicole Kidman. Cruise returned to her show in 2005 to talk about his new love, actress Katie Holmes. Cruise gained cultural infamy for jumping on Winfrey's couch in an enthusiastic display of his love for Holmes.
Tannen Maury / AFP-Getty Images
Then-Republican presidential nominee George W. Bush gives a kiss to Winfrey after appearing on her show on Sept. 19, 2000.
Evan Agostini / Getty Images
Winfrey is joined by Barbara Walters, left, and Diana Ross, right, at the launch party for her magazine on April 17, 2000, at the Metropolitan Pavilion in New York.
Touchstone Pictures via Getty Images
Winfrey co-starred with Danny Glover in the movie "Beloved," director Jonathan Demme's adaption of Toni Morrison's novel.
Akhtar Hussein / Getty Images
Winfrey arrives at the federal courthouse in Amarillo, Texas, in January 1998. Cattlemen filed a lawsuit against her for saying on her talk show that the U.S. beef industry could be at risk of spreading mad cow disease. The trial forced Winfrey to move her show to Amarillo for several episodes. She won that trial, but the cattlemen filed another suit a few weeks later. A U.S. District judge ultimately dismissed the case in 2002.
Mirek Towski / Time & Life Pictures via Getty Images
Winfrey ran in the Revlon Run/Walk for Women 5K to raise money for women's cancer organizations in 2007. She has been open about battles with weight and her love-hate relationship with exercise.
Ron Wolfson / Getty Images
Winfrey brought one of her furry friends with her to Ebony Magazine's "Celebrate the Dream: 50 Years of Ebony Magazine" event on Nov. 17, 1996.
Robin Platzer / Time & Life Pictures via Getty Images
Longtime boyfriend Stedman Graham has been by Winfrey's side at many awards shows, including the Daytime Emmy Awards. In 1987, her first year of eligibilty, she claimed three Emmys, including one for outstanding host and outstanding talk program.
Taro Yamasaki / Time & Life Pictures via Getty Images
In 1994, Winfrey consoled a distraught mourner during a segment of "The Oprah Winfrey Show" taped at Buffalo United Methodist Church, in Union, S.C., following the revelation that fellow townswoman Susan Smith drowned her sons, Alex and Michael, when she let her car roll into a local lake. The case drew nationwide interest.
On Nov. 16, 1988, Winfrey rolled out a toy wagon containing 68 pounds of fat on her show to illustrate how much weight she had lost. She credited her 68-pound weight loss to a liquid diet and exercise. Her goal was to fit into a size 10 pair of blue jeans for the first time. However, she quickly gained the weight back and has see-sawed ever since.
Ron Galella / WireImage
Winfrey strikes a pose with famed composer and producer Quincy Jones.
Winfrey co-starred with Whoopi Goldberg, second from right, and Rae Dawn Chong, right, in "The Color Purple" in 1985. She received an Academy Award nomination for her role as Sofia. She would later name her production company Harpo, another character in the film, which is also Oprah spelled backwards.
An 18-year-old Winfrey received the Miss WVOL award from the Nashville, Tenn., radio station in 1972. Winfrey rose quickly from local radio and TV reporter to become host of her own nationally syndicated talk show.