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Birth-control pill increases migraine risk

Women who take oral contraceptives have increased chances of suffering from both migraines and non-migraine headaches, a large new population-based study shows.
/ Source: Reuters

Women who take oral contraceptives have increased chances of suffering from both migraines and non-migraine headaches, a large new population-based study shows.

Some women have migraines during menstruation, when levels of estrogen drop, Dr. Karen Aegidius of the Norwegian National Headache Center in Trondheim, the study's lead author, told Reuters Health.

These women also are more likely to have migraines while taking oral contraceptives, she added, explaining that these pills can boost estrogen levels up to four-fold above normal, resulting in a particularly steep estrogen drop-off with menstruation.

Aegidius and her colleagues studied data from 13,944 women included in the Nord-Trondelag Health Study in Norway who responded to questions on both oral contraceptive use and headaches.

Migraines were 40 percent more common among women taking oral contraceptives, the researchers report in the medical journal Neurology, and non-migraine headaches were 20 percent more common.

However, the team could find no link between the amount of hormones contained in the pills and headache risk.

Physicians whose patients suffer headaches while on the pill could prescribe an estrogen patch to be used two to three days before menstruation, Aegidius suggested, so that estrogen levels wouldn't drop so steeply.

Another possibility, she added, is for women to stay on estrogen for three consecutive months, so they experience headaches just four times a year rather than every month.

Finally, she pointed out that the fall in estrogen with Mircette, an oral contraceptive available in the US but not Europe, is gradual rather than immediate, which could reduce headache risk.