The impotence pill Cialis appears to work even in men with spinal cord injuries, French researchers said on Monday.
Impotence often follows spinal cord injuries. Only about 25 percent of men with such injuries are capable of having sex, Dr. Francois Giuliano and colleagues at the Raymond Poincare Hospital in Garches, France said.
They found that Cialis tripled the number of times the men could have sex.
Their study, funded by Eli Lilly and Co, maker of tadalafil or Cialis, involved 197 men with an average age of 38 in France, Germany, Italy and Spain with spinal cord injuries.
After a one-month waiting period, in which no one got treatment, a questionnaire to assess sexual function found both groups had moderate erectile dysfunction, Giuliano's team reported in the Archives of Neurology.
Then 142 men were assigned to the Cialis group and 44 got a placebo for a 12-week period, taking no more than one pill daily as needed before sexual activity.
After 4 months, men taking Cialis were successful nearly half the time they attempted intercourse, while men in the placebo group succeeded only 16.8 percent of the time.
Cialis and similar drugs work by increasing blood flow to the genitals.
The researchers said the Cialis study achieved success similar to that found in studies of Pfizer Inc.'s Viagra or sildenafil and Glaxosmithkline Plc's Levitra or vardenafil, all of which improved erections in men with impotence after spinal cord injury.