Pope Francis cancelled several audiences on Friday due to flu, the first time his health has affected his role as leader of the world's 1.2 billion Roman Catholics.
The 76-year-old's well-being is under close scrutiny because of the shock February resignation of his predecessor Benedict, who said his health was declining and a stronger man could do the job better.
A Vatican spokesman said Francis had cancelled several meetings with cardinals and bishops on Friday morning, but would still take part in the ordination of a bishop in the afternoon.
"There is no reason for worry," Father Federico Lombardi said.