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By Alex Johnson

A "significant structure fire" injured at least 12 people as it swept through a hotel at Boyne Highlands ski resort in Northern Michigan, the resort said Sunday.

IMAGE: Boyne Highlands Resort fire
Firefighters battle a blaze Sunday at Boyne Highlands Resort in Harbor Springs, Michigan.Alex Childress via AP

None of the injuries was believed to be life-threatening, according to the resort, which is in Harbor Springs, 75 miles northeast of Traverse City. No conditions were reported, but one patient was flown by medical helicopter for treatment in a larger city, NBC station WPBN of Traverse City reported.

Firefighters and medical crews rushed to the resort after the fire was reported in the Main Lodge at 1:36 a.m. ET, authorities said. More than 110 guests were registered at the time, the resort said.

The fire damaged about 40 percent of the building, and much of the rest of the lodge was affected by fire, smoke and water, the resort said. The cause remains under investigation.

The resort remains closed, with no reopening date determined.