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Drugs found in Anne Heche's system after crash that left her in coma, police say

She is being investigated for possible DUI after her car slammed into an L.A. home, setting fire to the vehicle and the house.

LOS ANGELES — Actor Anne Heche, gravely injured and in a coma after a car crash last week, had drugs in her system and is being investigated for possibly driving under the influence, police said Thursday.

Heche, 53, was hospitalized in critical condition after the crash last Friday, which spread flames into a home in the Los Angeles neighborhood of Mar Vista, officials said.

"In preliminary testing, the blood draw revealed the presence of drugs," Los Angeles police said in a statement.

Police could not "comment right now on presence of cocaine, fentanyl or alcohol at this time,” they said. “That will be determined by the second test."

"The case is being investigated as felony DUI traffic collision," the statement said.

It is a felony investigation "due to female in the house" who was "engulfed in flames," police said. The woman living in the home has been identified as Lynne Mishele.

The woman’s lawyer, Shawn Holley, said in a statement, "Ms. Mishele is devastated by what happened to her on Friday — not only because she and her pets almost lost their lives, but because all of her property, including items of profound sentimental value, were destroyed."

Charred debris and caution tape are seen at the site where Anne Heche crashed into a home
Charred debris and caution tape Monday at the site where Anne Heche crashed into a home in Mar Vista, Calif. Chris Delmas / AFP via Getty Images

Heche was still in a coma and on a ventilator Thursday, surrounded by friends and family, at the Grossman Burn Center in Los Angeles. "Tests have been done, and doctors are evaluating whether certain surgeries can be done to improve her situation," a representative for Heche said.

Her 20-year-old son, Homer Laffoon, has been designated as her next of kin, the representative added.

Heche first came to attention on the soap opera “Another World" and later gained fame in films such as “Donnie Brasco,” “Volcano” and “I Know What You Did Last Summer.” She has also acted in “Chicago P.D.,” “Men in Trees” and other TV series.

Heche has said her relationship of over three years with comedian and talk show host Ellen DeGeneres — while groundbreaking as a high-profile same-sex romance in the 1990s — damaged her film career.

She most recently had a recurring role on the CBS legal drama “All Rise.”

She also hosts a podcast with public relations guru Heather Duffy called “Better Together,” in which they “celebrate friendship, and we believe that we can create more joy in the world by sharing our stories, stumbles, and triumphs.”

Diana Dasrath reported from Los Angeles and David K. Li from New York City.