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By Corky Siemaszko

From Chicago to New York City, brace yourselves for a big chill.

Some of the coldest weather this year is heading your way, and by the end of the week, wind chills in the Big Apple and much of the East Coast could be in the single digits, the National Weather Service warned.

"The big story over the next couple days will be the arctic air rolling in," National Weather Service meteorologist Frank Pereira told NBC News. "This could bring some the coldest air of the season. By Thursday, we could be looking at single digits across the Midwest, including Chicago."

Along with the cold, "we're going to see snow develop across the Great Lakes, Chicago included," Pereira said.

By Friday, the frigid weather will reach the East Coast.

Anthony Green, 9, left, throws a snowball Monday at Eric Babcock, 15, in Flint, Michigan.Mark Felix - via AP

"Northern New York and New England have the best chances for receiving significant snow," Pereira said. "It will be a messy, wintry mix to the south."

And it will be super cold.

"We'll be lucky if the highs climb out of the low 20s," NWS meteorologist Carlie Buccola said of New York City. "At night, we're looking at temperatures in the teens, and the wind chill will be lower than that."

By contrast, they'll be baking in Alaska, with highs in the 30s forecast for Friday in places like Anchorage.

So far, the coldest temperatures New York City has felt this year came on Saturday and Sunday nights, when the mercury hit 28 degrees, Buccola said.

Meanwhile, the NWS issued winter storm warnings and winter weather advisories for parts of the Great Lakes and the Northeast as a line of snow barreled east across the region, according to The Weather Channel.

High pressure was expected to move in behind it, bringing those shivering temperatures the forecasters are warning us about.