Updated at 10 p.m. ET: Mary Richardson Kennedy, 52, the estranged wife of Robert F. Kennedy Jr., was found dead at the couple’s home in Bedford, N.Y., her family confirmed Wednesday.
No cause of death was given. Andrea Mitchell reported on NBC's "Nightly News" that it was a possible suicide.
"We deeply regret the death of our beloved sister Mary, whose radiant and creative spirit will be sorely missed by those who loved her," the family said in a statement. "Our heart goes out to her children who she loved without reservation."
"We have no further comment at this time."
Kerry Lawrence, a lawyer for Mary Kennedy, told msnbc.com that he will not have any information about the cause of death until the autopsy report.
Mary was Robert F. Kennedy's second wife, with whom he had four children -- Connor, Kyra, William and Aiden. They married in April 1994, just one month after he divorced his first wife, Emily Ruth Black, with whom he had two children.
A wedding announcement in The New York Times said Mary Richardson was then an architectural designer for a New York firm.
In a statement from the Robert F. Kennedy, Jr. family, Kennedy was described as a “tremendously gifted architect and a pioneer and relentless advocate of green design who enhanced her cutting edge, energy efficient creations with exquisite taste and style.”
Robert filed for divorce in May 2010 after 16 years of marriage, the New York Post reported.
A press release from the Bedford Police Department said officers had responded at 1:36 p.m. to investigate a "possible unattended death" on South Bedford Road, NBC reported.
"Responding officers confirm that a deceased individual had been located inside an out building on the property," it said.
Robert F. Kennedy Jr., 58, is a prominent environmental lawyer. He is the son of Sen. Robert Kennedy and the nephew of President John F. Kennedy, both assassinated in the 1960s.
Bedford police declined further comment, but said they would make another statement early Wednesday evening, the Post reported.
The Westchester County Medical Examiner told NBC that it would conduct an autopsy and have the results on Thursday, and would not confirm or deny reports of a possible suicide until then.
Mary Kennedy had had trouble with drugs and alcohol and had two arrests around the time her husband filed for divorce, The Associated Press reported.
Kennedy was charged in August 2010 with driving under the influence of drugs, not long after she pleaded guilty to drunken driving when police reported seeing her car hit a curb outside a school near her home. Police said she had a blood-alcohol level of 0.11 percent -- over the legal limit of 0.08 percent. Her license was suspended.
She was arrested again a few months later in August 2010 for “driving while ability impaired with prescription drugs," according to Lawrence, who represented her in both assistances. He said they established that all of the drugs had been prescribed by physicians. The judge dismissed the charges.
The family statement said Kennedy was a co-founder of the Food Allergy Initiative, saying contributions may be made in her name.
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