Only one Republican broke rank to vote with Democrats: Utah Sen. Mitt Romney, who voted to convict Trump on abuse of power. The vote on the second article, obstruction of Congress, came down on party lines.
The outcome was effectively assured after senators on Friday voted against hearing witnesses, also largely on party lines.
Read the latest news and analysis below:
Romney says he will vote to convict Trump for abuse of power
Sen. Mitt Romney, R-Utah, announced he will vote to convict President Donald Trump on abuse of power, one of the two articles of impeachment he faces.
Romney is the only Republican to announce a vote to convict the president.
Romney said Trump was "guilty of an appalling abuse of public trust" and that "what he did was not perfect."
He called Trump's conduct a "flagrant assault on electoral rights, electoral security, and fundamental values" and "the most abusive and destructive violation of one's oath of office that I can imagine."
As he started to read his speech, Romney appeared to choke up with emotion.
"The president's insistence that [Joe and Hunter Biden] be investigated by the Ukranians is hard to explain other than as a political pursuit," Romney said. "There's no question in my mind that were their names not 'Biden,' the president would never have done what he did."
Romney said he knew he was certain to face backlash from the president and his supporters and said it was the most difficult decision he's faced. He added that the vote allows him to tell his children and family that he performed his duty "to the best of my ability."
“With my vote I will tell my children and their children that I did my duty,” Romney said. “What the president did was wrong. Grievously wrong.”
Kaine defends Pelosi, calls Trump a 'jackass'
Sen. Tim Kaine did not mince words during an appearance on MSNBC's "Andrea Mitchell Reports" on Wednesday to talk about Trump's impeachment and the State of the Union address.
The Virginia Democrat said that Trump cannot claim exoneration because his impeachment trial was a "sham" and called the president a "jackass" for not shaking hands with House Speaker Nancy Pelosi after his address Tuesday night.
"He’s going to be acquitted," Kaine said. "I don’t think it’s an exoneration because the Senate trial was such a sham."
He added, "The refusal to allow evidence will put an asterisk by this. So, yes, it is an acquittal, but if I were the president, I would want exoneration and I don’t think exoneration is what you get when you engineer a sham rather than a trial."
He also excoriated Trump for ignoring Pelosi's outstretched hand and in turn defended the speaker for ripping her copy of the president's speech at the end of his address.
"I said, well, wait, so, he won't shake her hand and he gives a Medal of Freedom to somebody who's called her every name under the book for years," he said, referring to conservative radio host Rush Limbaugh, who has consistently trafficked in sexism and racism.
"And he stands up there and lies about health care, but we're going talk about how she should respond? I mean, he can behave like a jackass, but we have to jump all over her back? I mean, I don't get the double standard."
Maloney on Collins acquittal vote: 'It's transparently nonsense'
Jones: Re-election battle 'never crossed my mind' in impeachment decision
Jones spoke to reporters following his announcement that he would vote to convict Trump.
When asked if he was worried about his re-election, Jones said, "No. It has never crossed my mind. Did ya’ll hear that speech? Did anybody hear that speech? It has never crossed my mind."
He added that he "did what I thought was the right thing to do. It had been coming together."
NBC News noted that Jeff Sessions, who once held Jones' seat and is now running to reclaim it, is already attacking Jones over his impeachment vote
"So?," he said.
Hoyer says Bolton could 'probably' give 'relevant testimony'
House Majority Leader Steny Hoyer said that impeachment will be “over today” and that he finds it “very regrettable what is about to happen” in terms of the Senate acquitting Trump without hearing from any witnesses or requesting documents.
Asked if the House will subpoena John Bolton to testify, he says the committees will make that decision if they will proceed on that but that “we think he probably has some relevant testimony to give.”
Pelosi explains why she ripped Trump's speech: 'A pack of lies'
House Speaker Nancy Pelosi tore a copy of Trump's State of the Union speech in half Tuesday shortly after he concluded his address in the House chamber. She addressed this moment in a meeting with Democrats on Wednesday morning, telling them that she "tried to find one page I could spare that didn’t have a lie on it" but that "it was a pack of lies."
Multiple sources inside the room told NBC News that Pelosi called Trump's address a "disgrace" and accused him of turning the speech into a "reality show."
"Last night, we saw the President of the United States shred the truth right in front of us, tear up the truth," Pelosi said, according to one aide in the room. "We saw him lie about pre-existing conditions, that he’s the champion when he’s in court suing for it."
According to the aide, she said that "tried to find one page I could spare that didn’t have a lie on it."
"I didn’t go in there to tear up the speech, and I didn’t even care that he didn’t shake my hand, in fact, who cares?," she said, according to the aide. "But I’m a speed reader, so I read – you know – I went like this through the speech. So I knew that it was a pack of lies. I knew it was a pack of lies, but I thought, ‘Well, let’s see how it goes.’ About a quarter through it I thought, 'You know – he’s selling a bill of goods like a snake oil salesman. We cannot let this – we cannot let this stand.'"
Fellow Democrats gave her a standing ovation for her remarks, the sources said.
Manchin says he 'agonized' over impeachment vote
Manchin said he has “agonized” over how he will vote later Wednesday on the articles of impeachment.
“I know my state and I know my people well,” Manchin said. “But I know this country well and I feel very strong about the decision I’ll make is going to be a very personal one.”
Manchin said he has not spoken to Trump nor has he asked any other moderate Democrats how they will vote. Asked if the Senate can work in a bipartisan way moving forward, Manchin said “we have to.”
“Last night did not give me the encouragement we need,” he continued. “We need to unite the country. The country needs to be united.”
Doug Jones, vulnerable Democrat, will vote to convict Trump
Sen. Doug Jones of Alabama, a Democrat who faces a tough re-election this year, said on Wednesday that he will vote to convict Trump.
"After many sleepless nights, I have reluctantly concluded that the evidence is sufficient to convict the President for both abuse of power and obstruction of Congress," he said in a statement, adding that, "the gravity of this moment, the seriousness of the charges, and the implications for future presidencies and Congresses all contributed to the difficulty with which I have arrived at my decision."
FBI director asked about Biden investigation
Appearing at an oversight hearing Wednesday, FBI Director Christopher Wray was asked if the president or the Justice Department has sought in any way to retaliate for the impeachment process by asking the FBI to investigate Joe Biden, Hunter Biden, or any member of Congress.
Wray said the FBI will only open investigations based on the facts or the law.
Nadler said, so no one asked you to do this, correct? Wray said, “No one has asked me to open an investigation” except based on the facts and the law.