Drew Barrymore started out as America's sweetheart, coming from a family legacy of actors, but the wild world of Hollywood sent her spiraling into drugs, alcohol and unstable relationships. Through it all, Barrymore has come out on top -- still making movies and proving that she's a star.
A pregnant Barrymore and Adam Sandler perform with Jimmy Fallon on "The Tonight Show" on Wednesday, Feb. 26, 2014.
Barrymore attends the Chanel Celebration of the release of her photo book "Find It In Everything" at Chanel Boutique in Beverly Hills, Calif., on Jan. 14, 2014.
Jennifer Lawrence and Barrymore hug at the 71st Annual Golden Globe Awards held at the Beverly Hilton Hotel on January 12, 2014 .
Drew Barrymore and husband Will Kopelman attend a basketball game between the Los Angeles Clippers and the Los Angeles Lakers at Staples Center in Los Angeles on Nov. 2, 2012.
Barrymore stars as Rachel Kramer in the 2012 film "Big Miracle," which is based on the 1989 book "Freeing the Whales."
From left, Robert De Niro, Barrymore and Kate Beckinsale attend the premiere of "Everybody's Fine" in New York on Dec. 3, 2009.
Barrymore and Justin Long are shown in a scene from the 2010 romantic comedy "Going the Distance."
Barrymore shows off her punk side and her new dark-dipped ‘do as she participates in a press conference for her upcoming movie "Whip It!" during the 2009 Toronto International Film Festival.
Barrymore, right, shows she knows how to roll with it in a scene from her 2009 movie “Whip It.” The actress, who plays tough roller-derby girl Smashley Simpson, attended roller-derby boot camp, where she and her fellow cast members learned rail checking and other classic derby moves.
Barrymore made her directorial debut in the 2009 movie “Whip It.” She tells People.com that the tough-as-nails story attracted her to the project and that she likes “movies about girls who are capable.”
The actress shows fondness for her “Grey Gardens” co-star Jessica Lange at the 66th Annual Golden Globe Awards. Barrymore, who plays Edith “Little Edie” Bouvier Beale in the HBO movie, worked with a voice coach for a year to nail down the correct accent.
The actress attends the HBO Films premiere of "Grey Gardens" at The Ziegfeld Theater in New York City. During the event, the star was spotted being affectionate with her ex-boyfriend Justin Long.
"I adore him," she told People magazine. "And I thank God that my friend supports me the way he does."
Barrymore plays Edith Bouvier Beale, the cousin of Jacqueline Kennedy Onassis, in the 2009 HBO film "Grey Gardens." It became HBO's most watched TV movie since 2004.
Barrymore began dating Justin Long after co-starring with him in "He's Just Not That Into You." The couple split after a year.
With an all-star cast, Barrymore takes on the role of a lonely newspaper ad sales rep in the 2009 romantic comedy, "He's Just Not That Into You." The film, based on a self-help book by "Sex and the City" writers Greg Behrendt and Liz Tuccillo, had several other A-listers, including Scarlett Johansson, left, Ben Affleck, Jennifer Aniston and Bradley Cooper.
The actress joins former President Bill Clinton as part of a Clinton Global Initiative event. The three-day event brought together global leaders to develop and then implement workable solutions to some of the world's most pressing challenges.
Barrymore, left, reads over and discusses lyrics with Hugh Grant in the 2007 comedy “Music and Lyrics.”
Barrymore and marathon world-record holder Paul Tergat pose with a portion cup during a World Food Program press conference at the Capitol on May 10, 2007 in Washington, D.C. Barrymore, who became the organization's ambassador in September 2007, said she couldn’t “think of any issue that is more important than working to see that no schoolchild in this world goes hungry.”
Barrymore, left, keeps her eye on the prize and Eric Bana’s hand in the 2007 movie “Lucky You,” which is about a gifted young poker player confronting his personal demons as he tries to win a world championship tournament in Las Vegas. Barrymore plays Billie Offer, an aspiring singer who just arrives in town and falls for Bana’s character, Huck Cheever.
She shows off her chic and glamorous side with an up-do and high-collar black shirt at Calvin Klein’s post-show party during Olympus Fashion Week in spring 2007.
In April 2007, the star became the new face of a CoverGirl cosmetics campaign. She is also the co-creative director for the campaign's TV commercials.
“Fever Pitch” is a 2005 adaptation of the 1997 film of the same name. In the romantic comedy, Jimmy Fallon plays a high school teacher and devoted Boston Red Sox fan who meets and falls for a successful businesswoman played by Barrymore.
Barrymore became a recurring voice in the animated TV comedy series “Family Guy,” first appearing as Brian Griffin’s simple-minded girlfriend, Jillian.
In 2004, Barrymore rocks out as Courtney Love in “A Very Special Valentine's Versace” skit on “Saturday Night Live.” She is still the youngest celebrity to have hosted the show (in 1982, at age 7).
"50 First Dates" is a 2004 romantic comedy starring Barrymore and Adam Sandler. In the film, Barrymore plays Lucy, a woman who suffers from anterograde amnesia. Realizing that he is beginning to fall in love with Lucy, Sandler's character Henry tries to find new ways to ‘meet’ her again every day, hoping she'll be able to remember him and have feelings for him.
The actress is honored with a star on the Hollywood Walk of Fame in 2004.
The stars align once more for the sequel, "Charlie's Angels: Full Throttle" in 2003. Barrymore convinced Demi Moore to join the film's roster.
"We were willing to do whatever it took," Barrymore told USA TODAY about snagging Moore for "Angels." "Demi was a huge battle for me that I had to win."
In 2001, she stars in "Riding in Cars with Boys," a film about a young girl who overcomes an unplanned pregnancy and a marriage to a heroin addict to eventually get her career on track. The movie is based on a 1990 autobiography of the same name.
People said it would never last -- and it didn't. Barrymore began dating comedian Tom Green, who made a cameo in her film, "Charlie's Angels." They married in July of 2000, after she stood by him while he battled testicular cancer. Five months later, the couple divorced.
Barrymore, right, kicks some on-screen butt with the help of Lucy Liu, left, and Cameron Diaz, center, in the 2000 movie "Charlie's Angels." The actress is also the executive producer of the flick, which is based on the same-titled '70s TV show.
In 1995, Barrymore was featured on the cover of Playboy and posed nude in the magazine. The actress wasn't exactly new to being seen in the buff. She had appeared naked in five of her films and, during an appearance on "Late Show With David Letterman," she climbed onto the host's desk and flashed him.
In 1995, Barrymore and partner Nancy Juvonen started the production company Flower Films, and 1999 comedy “Never Been Kissed” is its first production. In the film, Barrymore plays a 25-year-old Chicago Sun-Times copy editor who has never had a serious romantic relationship with a man.
In 1980s nostalgia film “The Wedding Singer,” Barrymore acts as the love interest for Adam Sandler’s character, a New Jersey wedding singer. The 1998 romantic comedy was later adapted into a stage musical with the same title.
Barrymore stars alongside Whoopi Goldberg and Mary Louise Parker in “Boys on the Side,” a 1995 film about three friends on a cross-country road trip. In the comedy-drama, she plays a pregnant woman looking to escape a violent, drug-dealing boyfriend.
Barrymore was briefly married to her first husband, bar owner Jeremy Thomas. They wed in 1994 in Los Angeles at his bar, The Room. Barrymore was 19 at the time; Thomas was 32. The ceremony was performed by a clairvoyant clergyman the couple had hired through a psychic hotline. Barrymore filed for divorce five weeks later.
In the 1994 movie "Bad Girls," Barrymore plays a former prostitute on the run, along with Mary Stuart Masterson, Andie MacDowell and Madeleine Stowe.
Barrymore goes the made-for-TV route in "The Amy Fisher Story" in 1993. The small-screen flick dramatizes the events surrounding Amy Fisher's teenage affair with Joey Buttafuoco and her conviction for aggravated assault for shooting Buttafuoco's wife. Barrymore, 18, plays the title character.
Alongside Ryan O'Neal and Shelley Long, Barrymore starred in "Irreconcilable Differences," a 1984 comedy-drama. The film was a minor box-office success and Barrymore was nominated for a Golden Globe award.
The actress steps up her bad-girl act in the 1992 thriller "Poison Ivy." In the film she plays a teen who seduces her friend's father and murders her mother, making it look like a suicide.
Barrymore's character Ivy is ranked sixth on the list of top 26 bad girls of all time by Entertainment Weekly.
In the 1992 crime drama "Guncrazy," Barrymore plays a teen who murders her sexually abusive father.
She chronicles her drug- and alcohol-fueled life as a Hollywood wild child in her 1990 autobiography, "Little Girl Lost."
"I started smoking cigarettes when I was 9½ ... I was also a club-hopper at 10, as much as a 10-year-old can be ... When I was 10½, I was sitting in a room with a group of young adults who were smoking pot. I wanted to try some, and they said, 'Sure. Isn't it cute, a little girl getting stoned?' Eventually that got boring, and my addict mind told me, 'Well, if smoking pot is cute, it'll also be cute to get the heavier stuff like cocaine.' It was gradual," Barrymore confesses in the book.
She dates Corey Feldman briefly, circa 1989-1990. At 16 years old, she gets engaged to Leland Hayward. After that relationship ends, she gets engaged to musician and actor Jamie Walter in 1992. That relationship fizzles out by 1993.
In 1987, Nancy Reagan meets with Barrymore after giving speeches in a White House forum to encourage kids to stay drug-free. Barrymore smokes marijuana at 10 and snorts cocaine at 12, and after a stint in rehab, she does coke in a New York nightclub bathroom.
In 1984, Barrymore starred in "Firestarter," a science fiction thriller film based on the novel of the same name by Stephen King. She plays a young girl who develops pyrokinesis.
After the release of "E.T.," Barrymore appears on "The Tonight Show" with Johnny Carson.
She screams her way to stardom with her breakout role in the 1982 Steven Spielberg film "E.T." At 7 years old, Barrymore played the sister of main character Elliot (Henry Thomas), who befriends, and later attempts to protect, an alien stranded on Earth.