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Mistrust of health workers, fear and weak health systems have combined to make Ebola a serious threat in West Africa, and it’s likely to spread beyond the three countries currently affected, the World Health Organization said Thursday. Cases are adding up quickly, with more than 779 people diagnosed, with 481 of them dead, WHO said in its latest update.

African health ministers agreed to step up their efforts against the virus after a two-day meeting that wrapped up late Thursday. That includes sending more experts, more supplies and coordinating efforts, WHO said. “The Ministers agreed that the current situation poses a serious threat to all countries in the region and beyond and called for immediate action,” they said in a statement. It’s time for concrete action to put an end to the suffering and deaths caused by Ebola virus disease and prevent its further spread,” said Dr. Luis Sambo, WHO’s regional director for Africa.

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- Maggie Fox