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A Malaysia Airlines jet with 295 people on board crashed Thursday in the hostile eastern region of Ukraine, near the Russian border, and the Ukrainian president said he could not rule out that it had been shot down.

NBC News could not independently confirm that the plane crashed, but Malaysia Airlines said on its Twitter account that it had lost contact with an aircraft, Flight 17 from Amsterdam to Kuala Lumpur. A Reuters correspondent in eastern Ukraine reported seeing the burning wreckage of a plane and bodies on the ground.

The site of a Malaysia Airlines Boeing 777 plane crash in the Donetsk region on Thursday.MAXIM ZMEYEV / Reuters