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9 best insect repellents: DEET and DEET-free bug sprays

Experts recommend ensuring any insect repellents you purchase are EPA-registered.
Husband and wife camping in beautiful nature. Child care during the covid 19 pandemic.
Experts said the key to buying insect repellent is ensuring products’ efficacy claims are backed up by scientific data.

During the warmer months, bug bites — like sunburns — are sometimes an unfortunate consequence of spending time outdoors. But bites from mosquitoes, ticks and other insects can be much more than just irritating or itchy — they can carry illnesses like malaria and Lyme disease, too. One preventative and protective measure you can take to avoid getting bitten is applying insect repellent. But figuring out which ones are actually effective can be confusing, seeing as the labels are often covered with complicated ingredients and jargon like “DEET” and “all-natural.”

SKIP AHEAD Best insect repellents | What is insect repellent? | How to apply insect repellent

To help simplify your shopping, we consulted experts about what’s important to pay attention to when buying bug repellent. Using their guidance, we also rounded up a handful of products you can use to prevent bug bites.

Our top picks

Best insect repellents for mosquitoes and more

Since DEET was the preferred active ingredient among the experts we consulted, we’ve included highly rated, EPA-registered DEET insect repellents with up to 30% of the ingredient, per expert advice. Recognizing that some shoppers might want DEET-free options, we’ve also included a few insect repellents that don’t use the ingredient, but are still EPA-registered and contain one of the active ingredients recommended by the CDC.

Best DEET insect repellents

OFF! Active Insect Repellent

This repellent is formulated with a concentration of 15% DEET, which amounts to six hours of protection, and it works against mosquitoes, biting flies, gnats, ticks, chiggers and fleas, the company says. The sweat-resistant spray is meant for outdoor activities like running and hiking. It’s earned an average 4.5-star rating over more than 760 reviews at Walmart.

Cutter Backwoods Insect Repellent

This sweat-resistant repellent features 25% DEET in its formula, which the company said protects for up to 10 hours. In addition to mosquitoes, this repellent is meant to ward off ticks, biting flies, gnats, no-see-ums, chiggers and fleas. It has a 4.6-star average rating from more than 1,000 reviews on Amazon.

Ben’s 30 Tick and Insect Repellent

This unscented spray is meant to protect against ticks and mosquitoes. The formula contains 30% DEET and is water-based rather than alcohol-based, which means that less of the product evaporates on skin as you apply, according to the brand. The spray nozzle also delivers a continuous mist, making it easy to cover any exposed skin. It has an average 4.5-star rating from more than 1,100 reviews on Amazon.

3M Ultrathon Insect Repellent8

This insect repellent, which contains 25% DEET, repels mosquitos, ticks, biting flies, chiggers, gnats, deer flies and fleas, according to the brand. The brand also says that it lasts up to eight hours and is splash- and sweat-resistant. The insect repellent has a 4.6-star average rating from over 985 reviews on Amazon.

Best DEET-free insect repellents

Repel Plant-Based Lemon Eucalyptus Insect Repellent Pump Spray

Repel’s insect repellent spray is made with lemon eucalyptus oil and protects against mosquitoes for up to six hours, the brand says. The lemon eucalyptus in the repellent is meant to be non-greasy so your skin doesn’t feel sticky when applying it, according to Repel. It has a 4.5-star average rating over more than 7,600 reviews on Amazon.

Sawyer Products Picaridin Insect Repellent

This repellent features 20% picaridin in its formula with up to 12 hours of protection against mosquitoes and ticks, along with eight hours of protection against flies, gnats and chiggers, the company says. The insect repellent comes in a pack of two and has a 4.4-star average rating from over 5,300 reviews on Amazon.

Cutter Lemon Eucalyptus Insect Repellent

Made with 30% oil of lemon eucalyptus, this bug repellent formula is meant to ward off mosquitoes for up to six hours, the brand says. It leaves a lemon eucalyptus scent on the skin but, isn’t supposed to feel oily, according to Cutter. It has a 4.4-star average rating from over 4,600 reviews on Amazon.

OFF! FamilyCare Insect Repellent II

This repellent is made with 5% picaridin, which is meant to provide protection for up to four hours, according to the brand. The pump spray is meant to protect against mosquitoes. Notably, it’s designed to work on clothing as well as skin and the company says it won’t damage cotton, wool or nylon. It has a 4.5-star average rating from over 1,733 reviews on Amazon.

Bullfrog Mosquito Coast Sunscreen SPF 50

This multi-tasker combines SPF 50 with insect repellent to protect skin from both the sun and bugs. The main active ingredient keeping bugs away is IR3535 and it promises to repel mosquitoes for up to eight hours, according to the brand. It has a 4.7-star average from over 650 reviews on Amazon.

How to shop for insect repellent

There are many products on the market that claim to repel insects, but they’re not all equally effective — and they don’t all have comprehensive data or research to support their claims.

“I think the key to choosing a proper insect repellent is to get something that you can do some research on and see effective scientific data that shows it works,” said Daniel Markowski, a technical advisor for the American Mosquito Control Association. “If something seems too good to be true, it probably is.”

With that being said, experts said there are a few factors you should consider while shopping for insect repellent, which we detailed below.

EPA registration

All the experts we spoke to recommended finding an EPA-registered insect repellent. The EPA has an online search tool that helps you look up registered bug repellents, and we used it to check the registration numbers on each of the products we recommended. All registered repellents offer protection against mosquitoes, but only some work against ticks.

DEET, DEET-free versus natural

Most experts we consulted agreed that DEET is the most effective active ingredient in an insect repellent. While DEET has gotten a bad reputation as being unsafe, experts told us there are no health risks associated with using it. “DEET is a controversial ingredient, largely because of misinformation. Some folks confuse it with DDT, an unrelated and banned compound in the United States, and others worry about reported neurological issues associated with DEET use that have been disproven by the medical community,” noted Erika T. Machtinger, an assistant professor of entomology at Penn State’s College of Agricultural Sciences.

Despite assurance from the medical community that DEET is safe, shoppers may consider looking for DEET-free insect repellents or ones labeled “natural.” There are some EPA-approved DEET-free insect repellents with other chemical active ingredients. Natural insect repellents tend not to be EPA-approved and incorporate ingredients found in, you guessed it, nature.

Which bucket a product falls into may impact what active ingredients it’s made with. Both the experts we spoke to and the Centers for Disease Control and Prevention recommend finding an insect repellent that’s registered with the EPA and features one of the following active ingredients:




Oil of lemon eucalyptus

Para-menthane-diol (also referred to as PMD)


The concentration of active ingredient in a product

Our experts told us that a higher percentage of an active ingredient does not increase your level of protection, though it does keep you protected for a longer period of time. In other words, the higher the concentration of an active ingredient, the longer the repellent will be effective, said Eva Buckner, the medical entomology extension specialist at the University of Florida. Concentrations can range anywhere from 10% to 100%, and according to Machtinger, repellents will generally work the same for the first couple of hours after they’re applied.

Markowski said most experts will advise against using a bug repellent that contains over 30% of an active ingredient. “You don’t really gain additional repellency from a product with a 70% or 100% concentration of active ingredients, but you are putting much more of the actual chemical on your skin,” he said. “Therefore, you’re much more likely to have adverse effects like allergic reactions.”

What is insect repellent?

The term “insect repellent” might seem broad — there are a lot of insects in the wild — but bug sprays usually cover mosquitoes, ticks or both, experts told us.

An insect repellent works by essentially jamming an insect’s radar, thus altering the insect’s ability to find a host. Experts explained that insect repellent compromises the ability of the sensory devices on the antennae to find a suitable host. A repellent affects senses like smell and taste, too, but it usually doesn’t kill the insect, according to Buckner.

What is DEET insect repellent?

Out of the three types of insect repellents, DEET insect repellents are “by far and away the most effective,” Markowski said. “It’s kind of the gold standard if you will.”

DEET was developed by the U.S. Army in 1946 and was approved for public use in 1957, so it’s been around for a while. As such, it’s “one of the most well-studied repellents on the market,” said Neeta Pardanani Connally, a biology professor at Western Connecticut State University (WCSU). While there’s “some disagreement on exactly how DEET works, the general consensus is that it interferes with the pest's host-finding ability — basically, they can't smell you anymore,” Machtinger explained.

By a wide margin, DEET is in most EPA-registered insect repellents — over 500 products feature it as an active ingredient (in second place is IR355 with about 45 products and in third is picaridin with more than 40).

What is DEET-free insect repellent?

Like DEET, DEET-free insect repellents formulated with the active ingredients we listed above are safe and effective, experts told us. However, they haven’t been around as long as DEET, which means experts haven’t had as much time to study their efficacy. Picaridin, for example, performs just as well as DEET when it comes to insects, but it hasn’t been studied as long, according to Buckner. Machtinger echoed this and added that though picaridin can be a “reasonable alternative to DEET,” it might “be more challenging to find in some places” — it can also be more expensive.

What is natural insect repellent?

The experts we consulted cautioned against using insect repellents that are branded as natural. Consumer Reports has also found them less effective compared to other types of insect repellents.

The EPA doesn’t allow the use of the terms “natural” or “naturally” on the label of any registered pesticide product “because the terms cannot be well defined and may be misconstrued as safety claims,” a spokesperson said. Natural repellents usually contain botanicals, which Consumer Reports noted are not registered with the EPA, and essential oils, which experts said don’t have as much scientific data to back up their efficacy claims compared to other active ingredients.

“It’s the ‘Wild West’ out there with natural products right now,” noted Connally, who oversees WCSU’s Tickborne Disease Prevention Laboratory. The natural repellent market can get especially complicated because some products with “natural ingredients” like clove and lemongrass oil are accepted as “minimum risk” pesticides, according to the EPA, but aren’t held to the same high standards as those that are registered to show “that a product does indeed have the repellency effects that the label claims,” Connally added.

Why is EPA registration important for insect repellents?

As we mentioned above, all the experts we spoke to recommend finding an EPA-registered insect repellent. But why does the EPA regulate insect repellents? While it might seem surprising, insect repellents are considered pesticides even though these sprays are meant to repel, rather than impair, insects. As such, most skin-applied insect repellents have to be registered by the EPA before being marketed to the public, and it’s up to the EPA to regulate them, a spokesperson for the agency confirmed.

The EPA reviews each repellent independently to confirm its efficacy before registration, the spokesperson added. A company applies for registration and the “EPA determines whether the product actually works and weighs the product’s benefits against its risks,” the organization told us. Registration means that a product has passed safety standards, is approved for use as the directions on the label state and can be sold and distributed in the U.S.

Not all insect repellents need to be registered with the EPA, though. Repellents with ingredients like citronella and cedar don’t need to be registered with the organization — while the EPA found they didn’t pose any health risks, they weren’t proven to be effective, either, “which is why typically we do not recommend these products,” explained Sonja Swiger, an associate professor at Texas A&M University’s department of entomology.

The EPA’s repellent database was last updated in June 2019 — the EPA confirmed that the products listed all remain registered and more recently registered repellents haven’t been added yet. A product remains registered as long as:

Registrants pay annual maintenance fees

The EPA isn’t forced to change the registration given emerging factors like adverse effects

The company doesn’t voluntarily cancel the registration

In 2020, the EPA registered a new active ingredient, nootkatone, the first one approved in over 11 years — it smells like grapefruit. While approved for use, there haven’t been any applications for products with nootkatone-based repellents to hit the EPA’s desk yet — the only registered product with the ingredient in it is made for manufacturing use, an agency spokesperson told us.

How to apply insect repellent

If the first step of preventing bug bites is buying an effective insect repellent, the second step is applying the product correctly, experts said. Many people are specifically concerned about mosquitos in the warmer months, and Markowski said “they’re very good at finding a host” during this time. ”Even if a quarter-sized amount of skin is not protected with repellent, they’re going to find it,” he said.

To ensure you’re fully protected, apply mosquito repellent like you would sunscreen. Spray or dollop it onto to any exposed skin and be sure to rub it in, and read the product’s label to find the suggested reapplication time. You don’t need to reapply insect repellent more frequently than the brand suggests unless you’re sweating or spending time in the water where it can wash off your skin, Markowski said.

Meet our experts

At Select, we work with experts who have specialized knowledge and authority based on relevant training and/or experience. We also take steps to ensure all expert advice and recommendations are made independently and without undisclosed financial conflicts of interest.

Eva Buckner is the medical entomology extension specialist at the University of Florida.

Neeta Pardanani Connally is a biology professor at Western Connecticut State University.

Erika T. Machtinger is an assistant professor of entomology at Penn State’s College of Agricultural Sciences.

Daniel Markowski is a technical advisor for the American Mosquito Control Association.

Why trust NBC Select?

Ambar Pardilla is a former reporter for NBC Select.

Zoe Malin is an associate updates editor for NBC Select.

Bethany Heitman is a contributor at NBC Select and a journalist who regularly covers topics like beauty, home and lifestyle. For this story, four experts were interviewed to gather their guidance and researched highly rated insect repellents.

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