A long-distance passenger train from Poland smashed into a collapsed bridge east of Prague on Friday, killing at least 10 people, railway officials said.
The crash occurred at about 10:30 a.m. (0830GMT) near the town of Studenka, about 210 miles from Prague, Czech Railways spokesman Radek Joklik said.
About 100 others were injured, he said. Rescue crews were scrambling to help victims at the scene.
Parts of the bridge near the town's railway station that had been under reconstruction fell onto the track as the train was approaching at speeds of more than 60 mph, Joklik said.
He said it was impossible to stop the train. The engine and first three carriages derailed.
The InterCity train from the Polish city of Krakow had been bound for the Czech capital, Joklik said. Some 400 people were on board, CT24 television said.