Earned Gray Hair By: Playing charming and likable scam artists/scoundrels in such films as "Out of Sight" (1996), "O Brother, Where Art Thou?" (2000), "Ocean's Eleven" (2001) and "Burn After Reading" (2008), as well as through exposing and campaigning for the Darfur crisis.
Earned Gray Hair By: Putting up with difficult men like Michael Corleone, Woody Allen and Jack Nicholson in such films as "The Godfather" (1972), "Annie Hall" (1977), "The First Wives Club" (1996) and "Something’s Gotta Give" (2003).
Earned Gray Hair By: Sweeping leading ladies like Lauren Hutton, Debra Winger and Julia Roberts off their feet in such films as "American Gigolo" (1980), "An Officer and a Gentleman" (1982), "Pretty Woman" (1990) and "Nights in Rodanthe" (2008).
Earned Gray Hair By: Trying to avoid horrifying death in such "Scream Queen" classics as "Halloween" (1978), "The Fog" (1980), "True Lies" (1994) and "Halloween: Resurrection" (2002).
Earned Gray Hair By: Reporting the hard breaking news and asking the tough questions as anchor of CNN's show "Anderson Cooper 360."
Earned Gray Hair By: Working hard as an actress, earning Emmys for "Prime Suspect" and an Oscar as Queen Elizabeth II in "The Queen" along the way.
Earned Gray Hair By: Saving patients' lives and seducing nurses or fellow residents as Dr. Mark Slone of ABC's hit TV show "Grey’s Anatomy."
Earned Gray Hair By: Being an Emmy-winning TV cook, running a Savannah, Georgia, restaurant with her sons, and publishing five cookbooks.
Earned Gray Hair By: Serving drinks and talking about his ex-baseball days at the bar where everybody knows your name in the classic TV show "Cheers."
Earned Gray Hair By: Being one of England's greatest actresses, earning an Oscar, two Golden Globes, and a Tony -- as well as trying to control 007 as M in the James Bond movies.
Earned Gray Hair By: Seeking revenge on those who attempted to kill him in such "mobster" movies as "The Godfather Part II" (1974), "The Untouchables" (1987), "Goodfellas" (1990) and "Analyze This" (1999).
Earned Gray Hair By: Forging a long music career that has garnered her 10 Grammys over 29 years, as well as suffering the devastating loss of music partner Gram Parsons, who died of a drug overdose in 1973.
Earned Gray Hair By: Fighting the dark side, hunting down replicants/androids and recovering important artifacts in such films as "Star Wars" (1977) "Blade Runner" (1982) and "Indiana Jones and the Kingdom of the Crystal Skull" (2008).
Earned Gray Hair By: Pinning politicians down with tough questions as moderator of NBC News' "Meet the Press."
Earned Gray Hair By: Rising from blue-collar background in Salt Lake City to a successful comedy and acting career (not to mention surviving criticism of her performance of "The Star-Spangled Banner" at a 1990 baseball game).
Earned Gray Hair By: First from working long shifts at the hospital as "St. Elsewhere" (starting in 1983) and then from conducting criminal investigations involving the U.S. Navy and the Marine Corps in "NCIS" (starting in 2003).
Earned Gray Hair By: Making political satire and sociopolitical commentary every week as host of HBO’s "Real Time."
Earned Gray Hair By: Working for civil rights with her late husband, actor Ossie Davis, as well as forging a distinguished acting career that has spanned some 60 years.
Earned Gray Hair By: Serving as the 42nd President of the United States from 1993-2001, writing his autobiography "My Life" in 2004 and campaigning with his wife Hillary during her 2008 presidential run.
Earned Gray Hair By: Governing the state of Kansas from 2003-2009 -- and serving as the 21st Secretary of Health and Human Services.
Earned Gray Hair By: Having to be funny every night as host of Comedy Central’s "The Daily Show."
Earned Gray Hair By: Winning eight prime-time Emmys (more than any other actress) and an Oscar for "The Last Picture Show" (1971) -- only to be eliminated from "Dancing with the Stars."
Earned Gray Hair By: Seeing the frightening clothes in peoples’ wardrobes before she helps make them over on TV’s "What Not to Wear."
Earned Gray Hair By: Being an undead vampire on "The Munsters" (her real-life portrayer, actress Yvonne De Carlo, died in 2007 at the age of 84).
Earned Gray Hair By: Letting it go that way for her performance as a domineering magazine editor in "The Devil Wears Prada" (2006) -- garnering her an unprecedented 14th Oscar nomination as well as a Golden Globe.