Breaking News Emails

Get breaking news alerts and special reports. The news and stories that matter, delivered weekday mornings.

Former Secretary of State Hillary Clinton reiterated on Wednesday that the 2012 attack in Benghazi, Libya was her "biggest regret" as head of the State Department, again addressing what could be one of the toughest questions she'll face if she runs for president.

"It was very, very painful and it was certainly the biggest regret I had as secretary of state," she said of the attack that took the lives of four Americans. "They weren’t the only people we lost but we lost them in such a terrible, senseless, terrorist action that it is just deeply sorrowful and went on for hours."

Clinton first called the attacks her biggest regret as Secretary of State back in January, which overshadowed her final days in the Obama administration. Republicans have accused the Obama administration of misleading the public about the motives behind the attack while President Barack Obama was campaigning for re-election.

Clinton supporters say conservatives are using the attack for political purposes to knock the potential Democratic presidential candidate.

The former first lady's remarks came during a speech at the Simmons Leadership Conference in Boston, Mass., where she encouraged women to "dare to compete."

“I think there are times in all of our lives when we are either given an opportunity or we see one that we can seize and we get nervous, we worry, we are not ready to dare anything,” she said. “But I hope you will and more than that I hope you will join me in committing the next generation of women leaders to dare to compete.”