"Because of that you inspired millions," he added.
Hussle, an Eritrean-American whose real name was Ermias Asghedom, was raised in the Crenshaw neighborhood of south Los Angeles. His debut studio album, "Victory Lap," was nominated for Best Rap Album at this year's Grammy Awards.
Congresswoman Karen Bass, who represents a district that includes L.A., tweeted Hussle's legacy "will live forever" in Crenshaw.
"He loved his community and it showed," Bass said.
Nipsey’s legacy will live on in all of those who continue to uplift, those who continue to inspire, and those who continue to lift as they climb.
My heart goes out to his family and the community that loved and admired him. 3/3
Police said Hussle was shot multiple times in the parking lot of Marathon Clothing on West Slauson Avenue in south Los Angeles at about 3:25 p.m. He was pronounced dead at a hospital. Two other men were also shot, and a suspect remained at large.
Investigators said it's not clear what the motive for the shooting was.
Recently he developed an interest in technology and community development.
Los Angeles Mayor Eric Garcetti's Crisis Response Team confirmed the news on Sunday night, saying, "Today we lost a great musician, Nipsey Hussle." It said it was "consoling and offering support to the family."
"Our hearts are with the loved ones of Nipsey Hussle and everyone touched by this awful tragedy. L.A. is hurt deeply each time a young life is lost to senseless gun violence," Garcetti tweeted.
Actor Jason Mitchell said in a tweet about preserving Hussle's legacy: "It's our obligation to let the world know who he was and what he stood for. Father, husband, entrepreneur, community leader, humanitarian."
Hussle and two co-owners opened Marathon Clothing in June 2017 as a "smartstore," complete with a smartphone app on which fans could buy exclusive content and products.
Los Angeles Police Commissioner Steve Soboroff said Sunday night that he and Police Chief Michael Moore had been scheduled to meet with Hussle and representatives of Roc Nation, Jay-Z's entertainment agency and production company, on Monday to "talk about ways he could help stop gang violence and help us help kids."
Open Wutang Family sends Love and Prayers to Nipsey and Family.